diff --git a/arch/arm/dts/Makefile b/arch/arm/dts/Makefile
index c160e884..79ed4ac 100644
--- a/arch/arm/dts/Makefile
+++ b/arch/arm/dts/Makefile
@@ -1259,7 +1259,8 @@
 	k3-am6528-iot2050-basic.dtb \
 	k3-am6528-iot2050-basic-pg2.dtb \
 	k3-am6548-iot2050-advanced.dtb \
-	k3-am6548-iot2050-advanced-pg2.dtb
+	k3-am6548-iot2050-advanced-pg2.dtb \
+	k3-am6548-iot2050-advanced-m2.dtb
 dtb-$(CONFIG_SOC_K3_J721E) += k3-j721e-common-proc-board.dtb \
 			      k3-j721e-r5-common-proc-board.dtb \
 			      k3-j7200-common-proc-board.dtb \
diff --git a/arch/arm/dts/k3-am6548-iot2050-advanced-m2.dts b/arch/arm/dts/k3-am6548-iot2050-advanced-m2.dts
new file mode 100644
index 0000000..9400e35
--- /dev/null
+++ b/arch/arm/dts/k3-am6548-iot2050-advanced-m2.dts
@@ -0,0 +1,121 @@
+// SPDX-License-Identifier: GPL-2.0
+/*
+ * Copyright (c) Siemens AG, 2018-2023
+ *
+ * Authors:
+ *   Chao Zeng <chao.zeng@siemens.com>
+ *   Jan Kiszka <jan.kiszka@siemens.com>
+ *
+ * AM6548-based (quad-core) IOT2050 M.2 variant (based on Advanced Product
+ * Generation 2), 2 GB RAM, 16 GB eMMC, USB-serial converter on connector X30
+ *
+ * Product homepage:
+ * https://new.siemens.com/global/en/products/automation/pc-based/iot-gateways/simatic-iot2050.html
+ */
+
+#include "k3-am6548-iot2050-advanced-common.dtsi"
+#include "k3-am65-iot2050-common-pg2.dtsi"
+
+/ {
+	compatible = "siemens,iot2050-advanced-m2", "ti,am654";
+	model = "SIMATIC IOT2050 Advanced M2";
+};
+
+&mcu_r5fss0 {
+	/* lock-step mode not supported on this board */
+	ti,cluster-mode = <0>;
+};
+
+&main_pmx0 {
+	main_m2_enable_pins_default: main-m2-enable-pins-default {
+		pinctrl-single,pins = <
+			AM65X_IOPAD(0x01c4, PIN_INPUT_PULLUP, 7)  /* (AH13) GPIO1_17 */
+		>;
+	};
+
+	main_bkey_pcie_reset: main-bkey-pcie-reset {
+		pinctrl-single,pins = <
+			AM65X_IOPAD(0x01bc, PIN_OUTPUT_PULLUP, 7)  /* (AG13) GPIO1_15 */
+		>;
+	};
+
+	main_pmx0_m2_config_pins_default: main-pmx0-m2-config-pins-default {
+		pinctrl-single,pins = <
+			AM65X_IOPAD(0x01c8, PIN_INPUT_PULLUP, 7)  /* (AE13) GPIO1_18 */
+			AM65X_IOPAD(0x01cc, PIN_INPUT_PULLUP, 7)  /* (AD13) GPIO1_19 */
+		>;
+	};
+
+	main_m2_pcie_mux_control: main-m2-pcie-mux-control {
+		pinctrl-single,pins = <
+			AM65X_IOPAD(0x0148, PIN_INPUT_PULLUP, 7)  /* (AG22) GPIO0_82 */
+			AM65X_IOPAD(0x0160, PIN_INPUT_PULLUP, 7)  /* (AE20) GPIO0_88 */
+			AM65X_IOPAD(0x0164, PIN_INPUT_PULLUP, 7)  /* (AF19) GPIO0_89 */
+		>;
+	};
+};
+
+&main_pmx1 {
+	main_pmx1_m2_config_pins_default: main-pmx1-m2-config-pins-default {
+		pinctrl-single,pins = <
+			AM65X_IOPAD(0x0018, PIN_INPUT_PULLUP, 7)  /* (B22) GPIO1_88 */
+			AM65X_IOPAD(0x001c, PIN_INPUT_PULLUP, 7)  /* (C23) GPIO1_89 */
+		>;
+	};
+};
+
+&main_gpio0 {
+	pinctrl-names = "default";
+	pinctrl-0 = <
+		&main_m2_pcie_mux_control
+		&arduino_io_d4_to_d9_pins_default
+	>;
+};
+
+&main_gpio1 {
+	pinctrl-names = "default";
+	pinctrl-0 = <
+		&main_m2_enable_pins_default
+		&main_pmx0_m2_config_pins_default
+		&main_pmx1_m2_config_pins_default
+		&cp2102n_reset_pin_default
+	>;
+};
+
+/*
+ * Base configuration for B-key slot with PCIe x2, E-key with USB 2.0 only.
+ * Firmware switches to other modes via device tree overlays.
+ */
+
+&serdes0 {
+	assigned-clocks = <&k3_clks 153 4>, <&serdes0 AM654_SERDES_CMU_REFCLK>;
+	assigned-clock-parents = <&k3_clks 153 8>, <&k3_clks 153 4>;
+};
+
+&pcie0_rc {
+	pinctrl-names = "default";
+	pinctrl-0 = <&main_bkey_pcie_reset>;
+
+	num-lanes = <2>;
+	phys = <&serdes0 PHY_TYPE_PCIE 1>, <&serdes1 PHY_TYPE_PCIE 1>;
+	phy-names = "pcie-phy0","pcie-phy1";
+	reset-gpios = <&main_gpio1 15 GPIO_ACTIVE_HIGH>;
+	status = "okay";
+};
+
+&pcie1_rc {
+	status = "disabled";
+};
+
+&dwc3_0 {
+	assigned-clock-parents = <&k3_clks 151 4>,  /* set REF_CLK to 20MHz i.e. PER0_PLL/48 */
+				 <&k3_clks 151 9>;  /* set PIPE3_TXB_CLK to CLK_12M_RC/256 (for HS only) */
+	/delete-property/ phys;
+	/delete-property/ phy-names;
+};
+
+&usb0 {
+	maximum-speed = "high-speed";
+	/delete-property/ snps,dis-u1-entry-quirk;
+	/delete-property/ snps,dis-u2-entry-quirk;
+};
diff --git a/configs/iot2050_pg2_defconfig b/configs/iot2050_pg2_defconfig
index d2bdeab..b206677 100644
--- a/configs/iot2050_pg2_defconfig
+++ b/configs/iot2050_pg2_defconfig
@@ -69,7 +69,7 @@
 # CONFIG_ISO_PARTITION is not set
 CONFIG_OF_CONTROL=y
 CONFIG_SPL_OF_CONTROL=y
-CONFIG_OF_LIST="k3-am6528-iot2050-basic-pg2 k3-am6548-iot2050-advanced-pg2"
+CONFIG_OF_LIST="k3-am6528-iot2050-basic-pg2 k3-am6548-iot2050-advanced-pg2 k3-am6548-iot2050-advanced-m2"
 CONFIG_SPL_MULTI_DTB_FIT=y
 CONFIG_SPL_OF_LIST="k3-am65-iot2050-spl"
 CONFIG_SPL_MULTI_DTB_FIT_NO_COMPRESSION=y
diff --git a/doc/board/siemens/iot2050.rst b/doc/board/siemens/iot2050.rst
index efe94a4..442d2ca 100644
--- a/doc/board/siemens/iot2050.rst
+++ b/doc/board/siemens/iot2050.rst
@@ -6,7 +6,9 @@
 
 The SIMATIC IOT2050 is an open industrial IoT gateway that is using the TI
 AM6528 GP (Basic variant) or the AM6548 HS (Advanced variant). The Advanced
-variant is prepared for secure boot.
+variant is prepared for secure boot. M.2 Variant also uses the AM6548 HS.
+Instead of a MiniPCI connector, it comes with two M.2 connectors and can
+support 5G/WIFI/BT applications or connect an SSD.
 
 The IOT2050 starts only from OSPI. It loads a Siemens-provided bootloader
 called SE-Boot for the MCU domain (R5F cores), then hands over to ATF and
@@ -70,7 +72,7 @@
  # configure for PG1
  $ make iot2050_pg1_defconfig
 
- # or configure for PG2
+ # or configure for PG2 or the M.2 variant
  $ make iot2050_pg2_defconfig
 
  $ make